Iris van Rooij is a reproductive epidemiologist and her research is focused on the etiology of congenital malformations, especially hypospadias, anorectal malformations, cleft lip/palate, and renal anomalies. This interest originates from her doctoral dissertation in 2003 entitled: "Etiology of orofacial clefts, gene-environment interactions and folate". She coordinates the multidisciplinary AGORA data- and biobank of children with congenital malformations or childhood cancer, with a collection of DNA, plus clinical and epidemiologic data, currently including over 4,000 patients and 2,000 controls with their parents (www.AGORAproject.nl). She integrates both genetic and pregnancy-related/environmental factors in her etiologic projects. Recently, she is partly shifting the focus towards pediatric care for these patients, including prognostic research and personalized healthcare and prevention.
National & International Personal Prizes & Awards
- 2012: Best Paper Award of the European Society of Pediatric Urology for the paper "Common variants in DGKK are strongly associated with risk of hypospadias" in Nature Genetics
- 2003: The International Centre on Birth Defects Award for the best paper on Birth Defects Epidemiology, Prevention and Public Health for 'Does the interaction between maternal folate intake and the methylenetetrahydrofolate reductase polymorphisms affect the risk of cleft lip with or without cleft palate?' in American Journal of Epidemiology