Adaptive nature of hidden metabolism in PNAS

Notebaart Richard 2014

Richard Notebaart revealed, using an evolutionary systems biology approach, that the hidden world of metabolism has the potential to provide the genetic basis for adaptation to new environments. This research has important implications for biotechnological and medical applications, such as understanding gain-of-function mutations in tumor development. Notebaart RA et al., Network-level architecture and the evolutionary potential of underground metabolism, Proc Natl Acad Sci U S A.111:11762-7, 2014.

 


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