Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

Swinkels Dorine

Iron deficiency is the leading cause of anaemia and is known to compromise immune function. In an international iron consortium, researchers from the Departments of Laboratory Medicine and Health Evidence analysed genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional cohorts (total up to 48,972 subjects).  Researchers identified several new genes associated with iron status and provide insight into how iron levels may be linked to the risk of metabolic disease.

Publicatie in Nature communications: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis -  Beben Benyamin et al, 2014.


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