A paper of Myrte Neijenhuis (Gastroenterology and Hepatology) about the development and validation of a disease-specific questionnaire to assess patient-reported symptoms in Polycystic Liver Disease (PLD) was accepted for publication in Hepatology. PLD is a condition characterized by multiple liver cysts. Progressive hepatomegaly can lead to symptoms and reduced quality of life. Treatment of PLD focuses on symptom improvement. Measuring PLD-related symptoms is a prerequisite to determine effectiveness of therapy. Neijenhuis and colleagues developed and validated a disease-specific questionnaire that assesses symptoms in PLD (PLD-Q) with input from patients, clinicians and experts in quality of life research. The authors show that the PLD-Q is a valid, reproducible and sensitive disease-specific questionnaire which can be used to assess PLD-related symptoms in clinical care and future research.
Development and Validation of a Disease-Specific Questionnaire to Assess Patient-Reported Symptoms in Polycystic Liver Disease
Myrte K. Neijenhuis, Tom J.G. Gevers, Marie C. Hogan, Patrick S. Kamath, Titus F.M. Wijnands, Ralf C.P.M. van den Ouweland, Marie E. Edwards, Jeff A. Sloan, Wietske Kievit, Joost P.H. Drenth
Hepatology. 2016 Mar 11.
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