Grant on systems toxicology to assure human safety without animal testing
Rick Greupink and Frans Russel
(Dept. of Pharmacology and Toxicology) are the successful
co-applicants of an NWO/ZonMW consortium grant of 1.6 M€.
The project will integrate molecular mechanisms and clinical data to support non-animal based hazard and risk assessment for chemicals and drugs, concerning cholestasis, allergic contact dermatitis and liver cancer as endpoints.
The consortium builds upon a strong public-private partnership, which is led by TNO, and in addition to RadboudUMC, consists of partners from universities of Groningen and Maastricht, RIVM, Jansen Pharmaceutica NV, and SimCyp Ltd.
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